Director, Medical Affairs

Structure Therapeutics develops life‐changing medicines for patients using advanced structure‐based and computational drug discovery technology. The company’s platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs. We are advancing a clinical‐stage pipeline of differentiated treatments focused on chronic diseases with high unmet need, including cardiovascular, metabolic, and pulmonary conditions.

Structure Therapeutics is led by an experienced group of international drug innovators and financed by top-tier global life sciences investors. The company has completed an initial public offering (IPO) in February of 2023. With offices in California and Shanghai, Structure Therapeutics has the benefit of being at the center of life science innovation in both the US and China and capitalizing on the strengths of each geographic location.

Position Summary

The Director, Medical Affairs is responsible for external scientific and medical engagement for Structure Therapeutics. This includes taking the lead for planning, developing, and tracking scientific and medical communications, developing messaging for key development programs, and supporting partnerships with the medical community for areas targeted by Structure’s portfolio. This will be an individual contributor role reporting to the Executive Director, Medical Affairs and Advocacy Engagement. This is a hybrid role that will require 3 days in the office (2 core days, 1 flex day).

Essential Duties And Responsibilities

• Lead activities for scientific and medical communications
• Oversee development and execution of cross-functional Publication Plans across all molecules
• Attend and coordinate coverage of scientific congresses including sessions of interest and sharing data and intelligence across company
• Develop and coordinate review of content for scientific congresses, including congress deliverables and medical education programs
• Oversee the creation and submission of scientific materials, including slide decks, congress posters, abstracts, manuscripts, through the MLR process, ensuring timely updates, regulatory compliance, and global consistency across therapeutic areas Establish formal publication policy adhering to ICMJE and other guidelines Develop clear and compelling messaging across portfolio that will resonate with key audiences ensuring consistency in messaging and alignment with Structure’s strategic goals Mentor global and local teams on effective scientific communication strategies, fostering a collaborative approach that supports global alignment with local execution
• Maintain effective and appropriate cross-functional communication and collaboration among internal stakeholders (both in China and US; Medical/Clinical, Preclinical, Regulatory, Program Management, Corporate Communications, Commercial, Legal) while maintaining full compliance with relevant company, industry, legal and regulatory requirements
• Manage medical writers for publications
• Drive partnerships with medical community
• Identify, build relationships, and liaise authentically with external key opinion leaders (KOLs) for medical societies, institutions, and medical organizations to support common initiatives
• Develop and implement KOL engagement plan
• Translate complex scientific data into impactful, globally consistent narratives that are clear, relevant and adaptable for external audiences such as healthcare professionals, regulatory bodies, and KOLs
• Be the trusted scientific partner to key external experts by conducting timely, appropriate and frequent scientific exchanges to enhance the understanding of the scientific and medical value of Structure portfolio
• Develop and execute advisory boards to gain scientific and medical advice for developmental programs
• Regularly present strategies to the Executive Leadership Team ensuring plans are aligned and approved
  

Requirements

Education

• M.D., Ph.D. or PharmD in a scientific discipline (or equivalent)
  
  

Experience

• 6+ years of experience in Medical Affairs or Clinical Development in the biotech industry, leading teams and engaging vendors/agencies
• Experience in a medical communications role strongly preferred
• Proven ability to lead and influence cross-functional teams without direct authority, driving strategic initiatives globally
• Demonstrated ability to translate complex scientific data into clear, impactful messages for diverse external audiences
• Hands-on experience managing the MLR review process and ensuring global compliance with varying regulatory requirements across different regions
• Understanding of Good Publication Practices and guidance (GPP, ICMJE), Sunshine Act, Pharma Code of Conduct
  
  

Core Competencies, Knowledge and Skill Requirements

• PC literacy required; MS Office skills (Outlook, Word, Excel, PowerPoint)
• Excellent writing skills
• Outstanding organizational skills
• Ability to work seamlessly across functions, build consensus, and influence
• Ability to work independently, with limited oversight
• Excellent verbal and written communication skills
• Ability to effectively collaborate in a dynamic environment
  
  

Travel, Physical Demands, and Work Environment

• Regularly required to operate standard office equipment (personal computer, photocopy machine, etc.)
• Ability to work on a computer for extended periods of time
• Regularly required to sit for long periods of time, and occasionally stand and walk
• Regularly required to use hands to operate computer and other office equipment
• Close vision required for computer usage
• Occasionally required to stoop, kneel, climb and lift up to 20 pounds
• Occasional travel to scientific meetings and advisory boards
  
  

The target salary range for this full-time role is $260,000 - $300,000 + bonus + equity + benefits. Structure Therapeutics determines salary ranges based on level and scope of responsibilities, as well as location. Individual pay is further determined by additional factors, including relevant experience, specific job skills, education and training. More details about the specific salary range for your location will be discussed with you during the hiring process by the StructureTx Talent Acquisition Team.