(Senior) Research Associate, Biochemistry

About Glyphic:

At Glyphic Biotechnologies, we plan to create the protein revolution for which scientists and researchers have been waiting. We are developing a massively parallel, single-molecule proteome sequencing platform that will transform life science discovery and usher in a new era of insights into human biology and disease. To date, we have raised >$50M from venture partners and non-dilutive grant funding to achieve our vision of next generation proteome sequencing.

What we are looking for in you:

Glyphic seeks a hands-on, adaptable Research Associate to support a wide range of experimental work spanning molecular biology, DNA conjugation, bead-based assays, and analytical instrumentation. This role is ideal for someone who is detail-oriented, enjoys learning new techniques, and thrives in a dynamic research environment. This position will execute high-priority experiments under the direction of a Senior Scientist on the chemistry team. The ability to manage multiple projects simultaneously and thrive in an extremely fast-paced environment will be necessary for success in this role.

Responsibilities:

• Prepare functionalized beads according to established protocols; execute variations on conjugation workflows as directed.
• Perform DNA conjugation reactions, cleanups (e.g., Zymo columns), and ligation protocols.
• Run and troubleshoot common analytical workflows, including HPLC, gel electrophoresis, and UV/Vis quantification.
• Assist with reagent preparation, sample handling, and basic lab maintenance.
• Maintain detailed and accurate electronic lab notebooks and inventory tracking.
• Adapt quickly to new procedures and priorities based on evolving project needs.
• Support cross-functional teams by contributing to routine assay and material preparation.
  
  

Required Competencies:

• B.S. or M.S. in Biology, Chemistry, Biochemistry, Molecular Biology, or a related field.
• BS+3 years of wet lab experience (academic or industry).
• MS+1 years of wet lab experience (academic or industry).
• Familiarity with molecular biology protocols such as DNA ligations, PCR, gel electrophoresis, and column cleanups.
• Comfortable operating instrumentation such as HPLC or willing to learn quickly.
• Strong organizational and documentation skills.
• Strong hands-on aptitude and attention to detail in executing complex assays with precision and consistency
• Proven ability to follow protocols accurately and troubleshoot experiments (with guidance)
• Team-oriented with strong communication skills and a flexible mindset.
  
  

Preferred Qualifications:

• Experience with oligo synthesis, solid-phase conjugations, or mass spectrometry.
• Familiarity with bioconjugation or DNA labeling techniques.
• Prior experience in a fast-paced startup or academic research lab.
  
  

Benefits and Perks:

• Employee Stock Option Plan
• 100% Health Plan Coverage for Employees & Dependents (Medical, Dental, & Vision)
• Employer Retirement Contributions to 401(k)
• Generous Paid Time Off
• Paid Maternity and Paternity Leave
• Health & Wellbeing Program
• Office Snacks and Beverages
• Regular Team Bonding Activities
  
  

We are an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. Individuals seeking employment at Glyphic Biotechnologies are considered without regard to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation.

Compensation Range: $75K - $115K