Research Associate
Tahoe Therapeutics
Date: 22 hours ago
City: South San Francisco, CA
Contract type: Full time

About Tahoe Therapeutics
Tahoe Therapeutics is a biotechnology company pioneering a fundamentally new approach to drug discovery — one that begins with the biology of real patients. Our Mosaic platform is the first to make in vivo data generation scalable, with single-cell resolution, allowing us to map how drugs affect patient-derived cells in the body across a wide range of biological contexts. We are building the world’s largest in vivo single-cell perturbation atlas — and using it to train multimodal foundation models that learn the context-dependent nature of gene function, disease progression, and drug response.By combining cutting-edge machine learning with the most biologically relevant datasets ever assembled in drug discovery, our mission is to find better drugs, faster — and bring them to more patients who need them.
Your role
We are seeking a talented and motivated Research Associate to join the Tahoe Therapeutics team. This position is laboratory-based and will require close work with team members to maintain cancer cell lines and support our Mosaic and Validation experiments. We are looking for a candidate that is a dedicated team player, capable of assisting with several projects at once, and one who thrives in a collaborative environment between multiple innovative individuals. Scientists that demonstrate self-motivation and enthusiasm for scientific bench work are strongly encouraged.
Qualifications
Tahoe Therapeutics is a biotechnology company pioneering a fundamentally new approach to drug discovery — one that begins with the biology of real patients. Our Mosaic platform is the first to make in vivo data generation scalable, with single-cell resolution, allowing us to map how drugs affect patient-derived cells in the body across a wide range of biological contexts. We are building the world’s largest in vivo single-cell perturbation atlas — and using it to train multimodal foundation models that learn the context-dependent nature of gene function, disease progression, and drug response.By combining cutting-edge machine learning with the most biologically relevant datasets ever assembled in drug discovery, our mission is to find better drugs, faster — and bring them to more patients who need them.
Your role
We are seeking a talented and motivated Research Associate to join the Tahoe Therapeutics team. This position is laboratory-based and will require close work with team members to maintain cancer cell lines and support our Mosaic and Validation experiments. We are looking for a candidate that is a dedicated team player, capable of assisting with several projects at once, and one who thrives in a collaborative environment between multiple innovative individuals. Scientists that demonstrate self-motivation and enthusiasm for scientific bench work are strongly encouraged.
Qualifications
- B.S. with 1+ year(s) of lab experience (undergraduate laboratory experience okay)
- Highly motivated self-starter with a demonstrated ability to overcome challenges and a strong work ethic
- Experience with tissue culture and cancer cell lines is a must
- Strong laboratory skills and experience with standard laboratory techniques
- Ability to multitask and manage time effectively
- Ability to work in a highly adaptive environment and learn new skills for changing priorities
- Demonstrated ability to work independently and in a team, coordinate tasks across multiple projects to meet deadlines
- Willingness to expand scope of responsibilities outside of initial job description
- Experience with CRISPRa/i/ko is a plus
- You must be legally authorized to work in the U.S
- Maintaining and propagating multiple cancer cell lines
- Develop and optimize experimental protocols
- Design and perform experiments in collaboration with scientists and bioinformaticians, under aggressive timelines
- Participate in technical discussions
- Support the larger R&D team in various lab/day-to-day operations and activities across the board
- Document experimental designs and results; maintain excellent records and data
- Unlimited Paid Time Off (PTO)
- HMO Kaiser Platinum and PPO Anthem Gold medical as well as vision and dental plans for both the employee and dependents
- Daily lunch stipend
- Company-wide events and offsite activities
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