Software Engineer/Senior Software Engineer
Genentech
Date: 8 hours ago
City: South San Francisco, CA
Salary:
$110,200
-
$253,100
per year
Contract type: Full time
The Position
A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.
Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximising these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide.
The Opportunity
At Genentech and Roche, we're at the forefront of a revolutionary transformation in drug discovery powered by AI and machine learning. Our "lab in the loop" strategy processes massive quantities of experimental data to train AI models that accelerate the discovery of new medicines. To enable this vision, we're seeking exceptional Senior Software Development Engineers to be part of the team building and maintaining our next-generation Therapeutic Molecule Registration (TMR) platform - a foundational component of our AI-driven drug discovery infrastructure. This platform will serve as the central nervous system for managing and integrating molecular data across our global research organization, handling hundreds of billions of records and enabling unprecedented scale in virtual molecule design and testing. As the volume of AI-generated molecular designs grows exponentially, our TMR platform must evolve to become a high-performance, cloud-native system capable of supporting rapid iteration cycles between computational design and experimental validation. You will be instrumental in consolidating our molecule registration systems into a single, harmonized environment, unlocking the full potential of our data and accelerating the development of life-changing therapies.
In the role, you will:
Software Development Engineer
Senior Software Development Engineer
Preferred Experience For Both Levels
Benefit
#ComputationCoE
#tech4lifeComputationalScience
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.
Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximising these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide.
The Opportunity
At Genentech and Roche, we're at the forefront of a revolutionary transformation in drug discovery powered by AI and machine learning. Our "lab in the loop" strategy processes massive quantities of experimental data to train AI models that accelerate the discovery of new medicines. To enable this vision, we're seeking exceptional Senior Software Development Engineers to be part of the team building and maintaining our next-generation Therapeutic Molecule Registration (TMR) platform - a foundational component of our AI-driven drug discovery infrastructure. This platform will serve as the central nervous system for managing and integrating molecular data across our global research organization, handling hundreds of billions of records and enabling unprecedented scale in virtual molecule design and testing. As the volume of AI-generated molecular designs grows exponentially, our TMR platform must evolve to become a high-performance, cloud-native system capable of supporting rapid iteration cycles between computational design and experimental validation. You will be instrumental in consolidating our molecule registration systems into a single, harmonized environment, unlocking the full potential of our data and accelerating the development of life-changing therapies.
In the role, you will:
- You will combine software engineering expertise with an interest in chemical and biological data management systems.
- You will work closely with Genentech Computational Sciences (gCS) colleagues, including our machine learning for drug development team, Genentech Research & Early Development (gRED) Drug Discovery teams including the Antibody Engineering division, and other teams across the Roche family of companies to identify, strategize, and productionalize high-impact applications from across the drug discovery and development pipeline.
- You will develop and maintain core features of our TMR platform
- You will write high-quality, testable code for chemical registration workflows
- You will design and implement RESTful APIs and microservices
- You will contribute to technical design discussions and architecture decisions
Software Development Engineer
- Bachelor's degree in Computer Science or related field (or equivalent experience)
- 3+ years of software engineering experience
- Strong Python programming skills
- Basic Java/Kotlin knowledge
- Experience with SQL databases
- Understanding of REST APIs
- Strong testing practices
- Cloud platform exposure (preferably AWS)
Senior Software Development Engineer
- Bachelor's degree in Computer Science or related field (or equivalent experience)
- 7+ years of software engineering experience
- Strong Python programming skills
- Ability to work with Java/Kotlin codebases
- Working knowledge of Postgres and SQL
- Experience with REST APIs and microservices
- Strong testing practices and test automation
- Experience with cloud platforms (preferably AWS)
- Understanding of CI/CD pipelines
- Experience with agile development methodologies
Preferred Experience For Both Levels
- Open source cheminformatics experience (e.g., RDKit, chemfp, Indigo, HELM toolkit)
- Chemical database cartridge expertise
- Familiarity with biological sequence alignment
- Chemical & biological structure notation expertise
- Familiarity with chemical structure canonicalization
- Molecular structure searching algorithm expertise
- Experience with scientific software development
- Familiarity with Docker and Kubernetes
- Experience with event-driven architectures
- Knowledge of security best practices
Benefit
#ComputationCoE
#tech4lifeComputationalScience
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
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