Associate Scientist

ABOUT SINGULAR GENOMICS

Singular Genomics is inventing at the forefront of genomics, one of the world’s fastest-growing industries. Our novel G4 benchtop sequencer is highly versatile and designed to rapidly produce accurate DNA sequencing results. We’re actively developing our PX instrument, the world’s first integrated single-cell analysis and spatial biology platform. Singular Genomics is committed to unlocking the potential of these core technologies to reshape the future of genomics.

We foster a culture of creativity and technical excellence, both catalysts for innovation. We celebrate diversity, emphasize collaboration and, as we rapidly mature, we are constantly looking at ways we can do better for our people.

Our Headquarters are located on the Torrey Pines Mesa, in La Jolla, California at the center of the biotech hub. Our Manufacturing facility is in Sorrento Valley. This role is based in our Torrey Pines location.

Responsibilities:  

• Collaborate closely with R&D to facilitate technology transfer of expression and purification procedures to manufacturing.
• Perform manufacturing protein expressions (bioreactor) and purifications (Akta systems) adhering to established protocols and document all process data clearly in batch records and power point presentations.
• Continuously evaluate and improve current manufacturing process and design. Focusing on scale up and optimizing the process by shortening, streamlining, improving robustness, or reducing labor and cost of the process.
• Author and review comprehensive process documentation, including standard operating procedures (SOPs), work instructions (WI) and batch records (BR).
• Provide support, guidance and mentorship to team members. Share knowledge and expertise to support their professional growth.
• Troubleshoot any technical challenges and propose innovative solutions for process improvement.
• Foster good work relationships with cross-functional teams, including R&D, reagents manufacturing team and quality control team.
• Stay abreast of the latest downstream processing technologies and techniques advancements. Evaluate, recommend, and implement new methods, equipment, or technologies to enhance processes.

Qualifications:  

• Degree in Life Sciences with relevant hands-on industry experience: B.S. 5 years, M.Sc. 3 years, PhD 1 year.
• Extensive protein expression and purification experience required.
• Proficiency in operating bioreactors and Akta purification systems highly preferred.
• Experience with enzymatic assay execution and protein conjugation is a plus. 

Job Specifications

• Strong work ethic and a proven ability to work independently or collaboratively in a multi-disciplinary team environment.
• Detail oriented with an ability to communicate clearly and effectively.
• Ability to professionally and technically support and mentor junior team members.
• Ability to temporarily lift 50 pounds.

The estimated base salary range for this role based in the United States of America is: $88,200 - $126,600. Compensation decisions are dependent on several factors including, but not limited to, an individual’s qualifications, location where the role is to be performed, internal equity, and alignment with market data. Should the level of the role change during the hiring process, the applicable salary range may be updated accordingly. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. 

Singular Genomics is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. 

Singular Genomics is committed to working with and providing reasonable accommodations to job applicants with physical or mental disabilities. Applicants with a disability who require a reasonable accommodation for any part of the application or hiring process can provide their name and contact information to our Accommodations team at [email protected]. Your request will be responded to as soon as possible.