Senior Director, Operations
Revance
Date: 5 hours ago
City: Johnson City, TN
Contract type: Full time

Job Summary
The Senior Director of Operations is a senior leadership role responsible for overseeing operational performance across pharmaceutical manufacturing and business functions. This position plays a pivotal role in ensuring compliance with Good Manufacturing Practices (GMP), optimizing semi-solid production processes, and driving operational excellence. The Senior Director partners with cross-functional leaders to align operations with strategic objectives.
Reporting to: General Manager
Location: Onsite, Johnson City Manufacturing Plant
Responsibilities/Essential Duties
Crown is a proud member of the Revance Portfolio of skincare offerings. Revance is a fast-growing global aesthetics and skincare company focused on providing innovative aesthetics and market-leading skincare offerings throughout every stage of life. With a differentiated portfolio of products spanning 60 countries, Revance meets the evolving needs of patients and consumers worldwide through continued innovation and commercialization of new products and treatments.
What Revance Invests In You
Revance is an Equal Opportunity employer. All qualified applicants will receive consideration for employment based on merit, without regard to race, color, religion, sex, national origin, disability, protected Veteran Status, or any other characteristic protected by applicable federal, state, or local law.
The Senior Director of Operations is a senior leadership role responsible for overseeing operational performance across pharmaceutical manufacturing and business functions. This position plays a pivotal role in ensuring compliance with Good Manufacturing Practices (GMP), optimizing semi-solid production processes, and driving operational excellence. The Senior Director partners with cross-functional leaders to align operations with strategic objectives.
Reporting to: General Manager
Location: Onsite, Johnson City Manufacturing Plant
Responsibilities/Essential Duties
- Strategic & Operational Leadership
- Define and implement operational strategies aligned with corporate goals.
- Lead long-term planning, process optimization, and continuous improvement initiatives across manufacturing and operations.
- Oversee semi-solid production manufacturing and packaging (creams, ointments, gels, lotions, etc.) with a strong emphasis on quality and efficiency.
- Ensure strict compliance with cGMP, FDA, and other regulatory guidelines.
- Establish and monitor SOPs, batch records, to meet quality standards.
- Partner with Quality Assurance to manage audits, inspections, and regulatory submissions.
- Drive productivity, cost-efficiency, and scalability across operations.
- Implement metrics, KPIs, and dashboards to measure performance and compliance.
- Standardize processes to support seamless technology transfer and scale-up activities.
- Lead, coach, and inspire a diverse operations team, including manufacturing, packaging and maintenance personnel.
- Build a culture of accountability, safety, and continuous learning.
- Develop talent pipelines and succession planning strategies.
- Work closely with R&D, Quality, Regulatory, Supply Chain, and Commercial teams to ensure alignment in production and operational priorities.
- Support technology transfer of new semi-solid formulations from development to commercial scale.
- Manage budgets, forecasts, and resource allocation within manufacturing and operations.
- Drive cost-optimization initiatives without compromising product quality and compliance.
- Bachelors degree in a related field required; advanced degree, MS or MBA preferred.
- 12+ years of progressive leadership experience in semi-solid operations, including GMP-regulated environments.
- Demonstrated expertise in semi-solid dosage form manufacturing and scale-up.
- Strong understanding of FDA, EMA, and ICH guidelines.
- Proven track record in leading manufacturing operations, audits, and regulatory inspections.
- Excellent leadership, stakeholder management, and communication skills.
- Deep knowledge of cGMP regulations and pharmaceutical manufacturing standards.
- Expertise in semi-solid formulation and production processes.
- Experience with LEAN manufacturing.
- Strong analytical and strategic decision-making abilities.
- Skilled in driving operational efficiency and business transformation.
- Collaborative leader with the ability to influence across functions.
Crown is a proud member of the Revance Portfolio of skincare offerings. Revance is a fast-growing global aesthetics and skincare company focused on providing innovative aesthetics and market-leading skincare offerings throughout every stage of life. With a differentiated portfolio of products spanning 60 countries, Revance meets the evolving needs of patients and consumers worldwide through continued innovation and commercialization of new products and treatments.
What Revance Invests In You
- Competitive Compensation including base salary and annual performance bonus
- Paid time off, holidays, and floating holidays that can be used for whatever you choose
- Generous healthcare benefits, Employer HSA match, 401k match, wellness discounts and much more
Revance is an Equal Opportunity employer. All qualified applicants will receive consideration for employment based on merit, without regard to race, color, religion, sex, national origin, disability, protected Veteran Status, or any other characteristic protected by applicable federal, state, or local law.
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