Biologist I

Company

At BioCryst, we share a deep commitment to improving the lives of people living with complement-mediated and other rare diseases. For over three decades we’ve been guided by our passion for not settling for “ordinary” in our quest to develop novel medicines. We leverage our expertise in structure-guided drug design to develop first-in-class or best-in-class oral small-molecule and protein therapeutics, led by the efforts of our team of expert scientists in our Discovery Center of Excellence in Birmingham, Alabama. Our global headquarters is in Durham, North Carolina and our employees span the globe across sites in multiple countries. We are proud of our culture of engagement and accountability that rewards people for innovative thinking and achievement of key objectives. For more information, please visit our website at www.biocryst.com or follow us on LinkedIn and Instagram.

Job Summary

Conduct routine laboratory maintenance and support. Assist inventory management in protein science. Support assay design, optimization, validation, and data analyses. Perform molecular and cell biology experiments. Troubleshoot and analyze data in support of drug discovery projects. Experience in techniques in molecular biology and cell biology. Good written skills to document experiments conducted daily. Must be comfortable with a fast-paced environment.

Essential Duties & Responsibilities

• Perform biological assays including enzymatic and cell-based assays, ELISA etc.
• Assist with biological and biochemistry assays for compound testing and biomarker assessment.
• Assist with the material inventory including proteins, antibodies, and plasmids in the protein science group.
• Assist with protein expression and protein purification within the protein science group.
• Prepare technical reports summaries, protocols, quantitative analyses, and maintain appropriate documentation.
• Lead a supporting role to the assigned project.
• Assist with early research and development program studies including method development and compound testing.
• Assist with pharmacodynamic (PD) biomarker studies including sample login, storage, and organization.
• Make detailed observations, analyze data, and interpret results.
• Advance multiple projects, identify priorities, and work in a fast-paced environment.
• Communicate results at internal meetings.
• Prepare reagents for routine work performed in Research Biology.
• All other duties as assigned.
  
  

Experience & Qualifications

• S. degree with 1 year experience preferred, or an equivalent combination of education and experience.
• Experience should be gained ideally in a molecular biology, biochemistry, cell biology, or toxicology setting, and must be comfortable with a fast-paced environment.
• Experience with various immunological techniques including but not limited to ELISA assays.
• Experience with protein expression, purification and characterization, and other protein-related assays.
• Experience with molecular biology techniques: molecular cloning, SDS-PAGE, Western blotting,
• Experience with other molecular biology techniques and cell culture.
• Ability to work independently after adequate training in role.
• Lead a supporting role to the assigned project.
• Good communication and presentation skills (oral and written).
• Self-motivated worker able to meet timelines set up by supervisor.
• Ability to distinguish priorities at work.
• Ability to navigate and be successful in a fast-paced, highly matrixed work environment.
• Good organizing skills, attention to detail, and willingness to support other team members.
• Ability to communicate effectively at all levels in the organization, verbally and in writing.
  
  

The statements in this position description are intended to describe the general nature and level of work being performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of responsibilities, duties, and skills required of personnel so classified. The manager may assign additional responsibilities and assignments from time to time.

BioCryst is an equal opportunity employer and is committed to providing equal employment opportunities without regard to age, race, religion, sex, sexual orientation, gender identity, national origin, Veterans status, disability and/or other protected class characteristics. Additionally, BioCryst is committed to achieving its business objectives in compliance with all federal, state and local law.