Intern, Bioprocess Development at Denali Therapeutics

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.

We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.

Denali is seeking an Intern for the Bioprocess Development group in Technical Operations. This position will be a hands-on laboratory position with a focus on optimizing conditions for Chinese Hamster Ovary (CHO) cell lines for expression of complex therapeutic proteins. The candidate will get exposure to suspension cell culture and single use bioreactors. This is an exciting opportunity to get an overview of biologics process development and manufacturing. The intern must be self-driven, organized, collaborative and able to communicate clearly and thrive in a highly dynamic and fast-paced environment.

Responsibilities

• Work under supervision of Denali scientists to design, execute and interpret cell culture experiments
• Perform and analyze shake flask and lab-scale bioreactor fed-batch production experiments
• Learn to use cell culture lab instruments such as such as Vi-Cell, Nova Flex2 and Octet
• Analyze results and present work to bioprocess development group
  
  

Requirements

• Candidates pursuing a BS or MS in Biology, Chemical Engineering or related field
• Familiarity with basic laboratory skills such as pipetting, material weighting, etc.
• Previous hands-on lab experience with mammalian cell culture including aseptic techniques is highly desired
• Demonstrated ability to organize, analyze and interpret experimental data
• Self- and results-driven, organized, resourceful, adaptable and collaborative
• Bold and creative thinker with a curious nature, eager to learn about the complexities of the business of healthcare and biotech
• Evident communication and analytical skills
• High degree of proficiency with the MS Office Suite or Google equivalent
  
  

The expected wage for this position based on the South San Francisco California office location is $22.11 to $27.40 per hour. Paid holiday time off is based on Denali's designated holidays. Interns who live more than 50 miles away from the office are eligible for an additional housing stipend.

Job Facts

• Start Date: Summer 2026
• Length of Assignment: 10 - 12 weeks
• Location: South San Francisco, CA
• Job Type: Paid Internship
  
  

This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.

Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.

Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.