RA/Sr. RA, Antibody Discovery

Prellis Biologics uses proprietary technology to 3D print lymph node organoids, which we are using to generate in vitro human lymph node cocultures for generating antigen-specific B-cells. We are seeking a Research Associate – Senior Research Associate, Antibody Discovery to join our Antibody Discovery team. In this role you will be supporting high-throughput antibody discovery efforts, particularly using single B-cell approaches. The ideal candidate will have a strong background in molecular biology, with significant experience in supporting end-to-end antibody discovery campaigns.

Key Responsibilities

• Perform high-throughput cellular biology techniques, including but not limited to, cell culture, Flow Cytometry, Fluorescence-activated cell sorting (FACS), and ELISPOT.
• Operate cell sorters and analyzers and perform routine maintenance.
• Maintain primary cell co-cultures using aseptic techniques.
• Help troubleshoot and contribute to protocol optimization for enhanced efficiency and increased throughput.
• Assist in the development and optimization of automation protocols for improved efficiency in molecular and cellular assays.
• Collaborate with cross-functional teams, providing technical support for various projects requiring automated workflows.
• Maintain accurate records of experiments, analyze data, and present results in team meetings. Qualifications:
  
  
  

Qualifications

• B.S in Molecular Biology, Immunology, Biotechnology, or related life science field with 4+ years of experience, or M.S. with 2+ years of relevant experience.
• Strong proficiency in maintaining primary cell co-culture systems.
• Proficiency in Flow Cytometry workflows and single cell sorting for sequencing.
• Experience with FlowJo or comparable analysis software is required.
• Ideal candidates will have prior experience in single B-cell antibody discovery workflows with an end goal of identifying novel therapeutic candidates.
• Ideal candidates will have prior experience with operating SONY MA900 cell sorters and MACSQuant analyzers.
• Strong organizational and time management skills to contribute to multiple projects in a fast-paced environment.
• Excellent communication skills and ability to document and present experimental results.