Payroll, Benefits, and HRIS Manager

Description

Description Position Description:

The Payroll, Benefits, and HRIS Manager is responsible for managing and overseeing OnKure's payroll processing, benefits administration, and Human Resources Information Systems (HRIS). This role ensures accurate and timely payroll processing, compliance with relevant laws and regulations, efficient benefits administration, and the effective use of HRIS for data management and reporting.

The ideal candidate will have strong analytical skills, attention to detail, and the ability to work collaboratively across departments.

Essential Duties And Responsibilities

• Payroll Management:
• Oversee the end-to-end payroll process, ensuring accurate and timely payroll processing for all employees
• Maintain payroll records and ensure compliance with federal, state, and local payroll, wage, and hour laws
• Manage payroll taxes, deductions, garnishments, and any other relevant payroll processes
• Reconcile payroll reports and resolve any discrepancies or issues that arise
• Collaborate with the Finance department for payroll-related financial reporting, audits, and equity benefit processing and reporting
• Respond to payroll inquiries from employees and resolve any payroll-related issues
• Benefits Administration:
• Manage and administer employee benefits programs, including health insurance, retirement plans, wellness programs, and other voluntary benefits
• Ensure compliance with benefits regulations such as COBRA, HIPAA, and ERISA
• Oversee the open enrollment process, including communication, education, and system updates
• Coordinate with benefits providers and vendors to resolve any issues or discrepancies
• Analyze and review benefits programs periodically to ensure competitiveness and cost-effectiveness
• Assist employees with benefits-related inquiries and claims issues
• HRIS Management:
• Oversee the maintenance and integrity of employee files and data, ensuring accurate data entry, system updates, and user access
• Generate and analyze HR reports, metrics, and dashboards to support decision-making and strategic planning
• Train users on HRIS functionalities and best practices
• Work with HRIS vendors to troubleshoot and resolve system issues or enhancements
• Ensure data privacy and security within the HRIS in compliance with relevant regulations
• Manage employee files

Preferred Experience and Qualifications:

• Bachelor’s degree in human resources, business administration, finance, or a related field, or equivalent experience
• 5+ years of experience in payroll, benefits administration, and HRIS management
• Strong knowledge of payroll laws, tax regulations, and benefits compliance
• Proficiency with HRIS platforms (e.g., ADP, Workday, SAP, or similar)
• Advanced Excel skills and experience with payroll software
• Excellent analytical, problem-solving, and organizational skills
• Strong communication and interpersonal skills
• Ability to manage multiple priorities in a fast-paced environment
• Certification such as CPP (Certified Payroll Professional) or CEBS (Certified Employee Benefit Specialist) is a plus
  
  

About OnKure:

OnKure, Inc. is a clinical-stage biopharmaceutical company focused on the discovery and development of precision medicines that target biologically validated drivers of cancers that are underserved by available therapies. Using a structure- and computational chemistry-driven drug design platform, OnKure is committed to improving clinical outcomes for patients by building a robust pipeline of small molecule drugs designed to selectively target specific mutations thought to be key drivers of cancer.

To attract the very best talent, OnKure offers a generous compensation and benefits package that includes competitive pay, performance-based bonus opportunities, stock options, insurance coverage (health, dental, life, and disability) for full-time employees, self-managed paid time off, and a 401(k) plan with company match. Candidates who live in or are willing to relocate to the Boulder, CO area are preferred.

The expected annual compensation range for this role, based on experience, is $85,000-$110,000.

OnKure is an equal opportunity employer and welcomes all job applicants. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, protected veteran status, disability, or any other protected factors.